Editorial Commentary: PRP: Platelet-Rich Plasma or Promising but Rarely Proven?

Platelet Rich Plasma ( PRP ) Therapy

Molloy, et. al., (2003) address specific growth factors encountered in ligament and tendon healing. After reading about the factors found in superficial wounds, above, these should appear familiar, including: Platelet derived growth factor (PDGF)—produced shortly after tendon injury, stimulates production of other growth factors such as IGF-1, and is involved in the tissue remodeling phase of h...

Tissue Engineering: Oromaxillofacial reconstruction with platelet rich plasma (PRP)

Platelet rich plasma (PRP) for facial rejuvenation

As a result, human growth factors have been widely studied and today there are clinical applications of several individual growth factors. Examples are a keratinocyte growth factor (Kepivance®, Sweden) for oral mucositis and platelet derived growth factor (Regranex, UK) for non-healing diabetic wounds. However, these exogenous growth factors, when applied outside their normal environment, may h...

Platelet-rich plasma (PRP) for knee disorders

Platelet-rich plasma (PRP) is an autologous blood product with platelet concentrations above baseline values. The process involves the extraction of blood from the patient which is then centrifuged to obtain a concentrated suspension of platelets by plasmapheresis. It then undergoes a two-stage centrifugation process to separate the solid and liquid components of the anticoagulated blood. PRP o...

Intraarticular Injections of Platelet-rich Plasma (PRP)in the Management of Knee Osteoarthritis

  The clinical use of PRP therapy in the practical setting of orthopaedic fields is increasing partly because of the accessibility of devices that are used in outpatient preparation and delivery. Another reason is the strong advertisement of PRP procedures as the ultimate treatment and novel technology for knee problems by a few orthopaedic surgeons based on claims of abundant scientific eviden...